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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd76550b9aeeed130db5f14796c6e6413b647de3545ad10593d4c262bfa46b4e9' 
  AND token = 'bj/wKnOLaG1DhZQihXlD8M5gqKonroCijg3uldfq0Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}