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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2751f77d7e03bb6cda59f1b030a30e02f1f260258fbe4629bfdd6c628d59df9b' 
  AND token = 'ODvT2W1v2hDxYGHuotHBWa3K1M2k+bxtSzNU5XNaD9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}