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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b16b29b6cfc3bf3b7d2c7be47ee44dea6578d67bb0d3bda4669f842abddede5' 
  AND token = 'cVN6ku7gjGC6iz93usrjKsNV72ti1WzSrUtBe62NLZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}