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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4573ad021b709e42833d25329f518eb617abc74fb9c27b9a576a7410e9e74dc3' 
  AND token = '+TRmY2o1WhHBViIcZPE+ToDRnIDSj3TnNoQIexALfDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}