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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e85c79f39931e34d73927ed5d537fb50ea9d14a1ca6461b41548329df2644920' 
  AND token = 'lG2n5GoKOPigYobo1+8EwEz5IPNQAinhThZ3VbwbNC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}