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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1eaab1c5e9e935b38eb3e61b2cd56f634e3635d2ac5aa9c34f09faab7fe549' 
  AND token = '/6dTVU4oAKSlbbZ88NqwfT3PRi1pFMFe5sSs7Aj9w1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}