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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0003395ef10279c749ac5e7f357895196cce12c868f84a58c2c8884d4f50d5cf' 
  AND token = 'ewfYNMqWoF+ibsrYwfMTdrLrsVGwvoL7Jdpwb5W1/3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}