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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9221d2089484a0db30e7e129547fda0430e565fe77c2f90df207fc2435e5a1f3' 
  AND token = 'sUCyPPWA/Iq+5YBiBcoQqZnDSGajPLmnTi3X/Ii5ke8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}