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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea2b7ef63d2fba1f5a5444801850357040994755e50240e6ee5bcaa9c0e57ba' 
  AND token = 'tojfZS7pDKI3KV4ZbTCYtbgCLDAs+rUDusn64g5vizo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}