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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec1d9c9f09b7b9b7a3a0993fbb4e4fda644afd272d1509efba70cff73f6f8f1' 
  AND token = 'JX59AqXLsPuPDskBH/gEO4AhhuxA9mftxqQFE6JYiw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}