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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b980e4122f86fa8b227cb90e0338cdfd939a3896dca91214f33d15e95a0464' 
  AND token = 'XLIHChKQZsnSbnhwOkg/1y2ytG6lG5gZNfrSRBocUgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}