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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da40fe246dfcf4e1586b1e83a4a613947ffe32daf4d6f545bf3f2d7f2d00c913' 
  AND token = '+H6S7aGEdnSa1GTBuGYZPtybVadLNu6+/mb/SXBDAuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}