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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730ecb63ef816e06f1c05702735f5e242792e024904741074e82805c2caa218e' 
  AND token = 'vkDGOiS+5pJKGo1neTsEwAFhx2OIrdunLSUj8am9Gm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}