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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b124c8f8157f8346fe38ea9d29aa79ebdf600b2cb8b2f57de18d77161582748' 
  AND token = 'kOygGuNf+gPES5j7BIluLnZZZkgOUCC7g2eizMK1hsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}