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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dbc8eae0ddbb0d42a80da80a456f19f00c294a17b833e6576541a639d0ac630' 
  AND token = 'gYBkokq4Kq8CktdGYg6bF6/aGMYy6lH+AQ0bCR9Jo38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}