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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcb932ae40370f2c188ba2a52a64b6e174aed5518fcb3013a59cb5e2c629db9c' 
  AND token = 'FVwnuSAJ+pJDnlEQVPje2J58MCJWEbVWJlKEID8Hkis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}