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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45852f43c2a84c099fafd11fecb24a28ab62a5f143dbb3c3b1272d6b2de1a55b' 
  AND token = 'cF2WxvGf2aabeR7672i6BgPElpAfeIaqIRPm21aLGK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}