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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aa901271c7e0cb6eb2bff93b8be7faa0490e1f7ecf797695e1b661a25ebbcd0' 
  AND token = '8il8Iy9qUYQhcDi3MQx86CJsW1qRMfFFD4XJhlVey1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}