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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b90883213ee84312fe21cfa642740504dfb2915640c2545b705237efdcb91282' 
  AND token = 'cq85aELDKDZoOJr1pgo0LyWntlMAwWbDN/r4R+kMcZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}