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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9bcfbcb79ee766ed1c5622204bf208c53641a68c69e207b83861224e5b40f36' 
  AND token = 'e1qOVL8UPD0wkND22CdrK3VS8jdXd2v58wxsWezXBIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}