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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e54dc319e8795a778b752e3626f3e0fdca3a610382e59c728c69c06ade4a80' 
  AND token = 'okwIfWdogAbpPL6G06s3jWObwU8+pq1npm2hkeqfsyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}