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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e237725b5c317a2b3ee9d74f21b997b27d424c190a13ac38d3ecda2430680493' 
  AND token = '6EIxzCchE7XZdzwgcwxLAwwVc/VtwVhHti3wNl1s4y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}