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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18fd6c39c7ec4052a1883aa991ba5ff707c52e72db90dcc3c548b297531a5375' 
  AND token = '13iFiWRKcFPndiNaqxFst9Bhf5aLVfLM5aSbkHZQ/UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}