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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d3ac209101f47c8b736850235ab7bd8491a6cd8e5a1245df71b3e9c69df5f6b' 
  AND token = '/X8GTilgSKim4Nszr9EcfFpQwoFy8Ofq6E4dG/rwlbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}