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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f51c0047df0bde1421c4c5bc9690e5aaf148a0d0ac9d15f13caa0ac75c6ef72' 
  AND token = 'EHwN1M+5fJ0vJJV8gAgO/leQ+X5qoJOWu/IxL7L62wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}