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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af08864359861324d90c2552504e26c60644335a5f8eaa0ac4e225de67f2bfe2' 
  AND token = 'uzVMt0gjQey2tr9WPcrZud2dhzqIm7i3BD4AdiEU4Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}