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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f591ad442ad0408a8ee69b0a7dd1128f2e22a837d77bdb1ffdd7ae9248ba476' 
  AND token = '757Zk7zyQpJNyOIk/HCjf7Lo204myyxLcEowlOnO6FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}