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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49598c0cddfe0e706bb587b0db6f37095b8613626b18722ff051e5513a1ecdf6' 
  AND token = 'xqVXp78QUtpOvckLxI8yEAFBwfVkqYnNQq6OacN1lco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}