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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a257c23e85281530d00af6055b5764080dbd403de4775613b0e41fd39ed1afad' 
  AND token = 'EnJ6yQ+e9c3cFxZlw+LcSK4yWM9Qdmb7B2plbaZLYzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}