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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6224c9dd1754e19397b7e030d9001de6d41963775c12528422c3fa0fdff649dd' 
  AND token = 'ItGMGO1xO6O1OtUSfcSONdJnOHceiMOATNxl1TIXL9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}