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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f780d14639e742166e7a647b1ff9d5b445545c11ba21b6011fdeb28c7d3f0511' 
  AND token = 'R1eJHfufiEGk9ranbGSZJjL6HRcyG9cQ1wNRTisd3M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}