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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21162dcaee7ab053876cbbda486a8a922a9725e9a1e6ba69af73b2392c5fbb04' 
  AND token = 'THUVvWj0aiQet5hnGdxAZ1Ndj2b4ifzZUQ2yzPxSczE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}