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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b70029cfa494cadf53ce20af23e3b7a4933d143f75eed1d2dbba6c54f950ee1' 
  AND token = 'rnp1c0zBpPPh+Z1MLuRS5fnRlM4BcmkmWZBXpcozxwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}