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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b5fa3747d0b1164ff3c1ae2e47edbf69d5af5a2149f5f1b06bf4856f531652' 
  AND token = 'vtjMQP49Kc8vMCssSkMcJK8gp0gAjdhUdkhmYXa9fVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}