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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df6eb7ccd9426446bdcbfb7754bdeeefdf042ebf7d902e487df2e5f8421b8b2' 
  AND token = 'n1mtwPmtkOYQ1/h2QgyIt7F3aUergevbzLS15hPXxOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}