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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45de6eca93111c59a5ad8b0b351c43c1844b6190dffa4c14bdc830f7a0f7c337' 
  AND token = '1k2zDLHi52S/HT88uegSzi5KB+JTYBAZtd71MolCqQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}