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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f226a0fcf1177bb5dccdce8a801da34afefaf13722016d37a05fd089660c0ed' 
  AND token = 'cC/5YsYErSRcKu0z8aajPeG4+OSkHb04CZ1+YlQOW6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}