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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2daf363d8cc24e1e791a2efdeb359848fa29027503c4dba657ec05b25a0533fa' 
  AND token = '4JgwO9iLEaaal+MxM+x6EpvnblM11GJKx7uRv6m6PvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}