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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cfec6c23fd0996e4ae2cab64bbe50ae7b01fedd9722287584e63a90d225c79' 
  AND token = 'I4gRpRHihRW/5qWv1rSxAbK1aO0PL9bRJDNs3gOeeNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}