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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a3d8dc3029d621ad7fbc9642f45566a121c60c5ccbb13be5a5515f80a053d4' 
  AND token = 'WFkpAnD275sf9Tr9PGc+gMJj+eSJ6pMRKXmhRsahnTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}