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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b3e49efe03c491b108d1b455d48af4f4ac9c21c59645f209669f6ee79fa6fd' 
  AND token = 'y6ZtFeM/0B9Tb/2QwDFAi22Bsklma8GwLLaJa/pcQgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}