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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e3009a75d1d57a400025845aeb52fd042718c0e81d6d0492ea7e16d24b4f72' 
  AND token = '+Wsdhjc8G1Cg674A+J8q5xEahLyWS4IvI/RJyQO6B+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}