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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '760d7e3f4f49b3d96d561ff116e6784427c9cc43767879e1dcdd54056a6bd9d6' 
  AND token = 'PzilAiMetFzvy5+cFKs3IzZ6BDXCiJKLTK1+SyaN2aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}