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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad075496c9a36eb2dff1d339c2d9d5185d844f960f561d443fdeb0b0ed793b77' 
  AND token = '7lLPXX97vnJBfiRKRYoWlU1vKR47L26JD4XUNiIOKu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}