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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b8de3fc1c111448c8ac7863945f24a7c476d27aeae2fcd52d512b97e31f4d2' 
  AND token = 'FmUomz8N9htBicj2JA0d57uYomB0A1CdphMoOYITknc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}