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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e33583abdcecf198fde2f264c989e3480ad5a81bb1d31884b9ac850455b43f' 
  AND token = 'UC4EcKaFHu6vmdb0Bs2CYuZ7d5bUz+7sOil0Dz3XG44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}