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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd99461206aa4675efb1ee76e36393793742234ff3bd36d30136be9bad11306f8' 
  AND token = 'ZtYo+MEUTjfH/iO6D6BOLw6eyDeb+SSRRKh0QaKM5Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}