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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8310a55ca9b76d2f3df48e802fac1c7493655260de536b5f24f1744a1c25012d' 
  AND token = '5Z7RLhu9LYTKpb9X1sT1bt6pANdr+5SShI7JLU07v6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}