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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0f525f76659304740b0759d7260d26f85a172b8e18884c53967ba493ba44526' 
  AND token = 'KpfCqZDrhyj1xqHl9dGO8RZJIRCcqkeNEsutRrsJDOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}