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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d9a21601d620c4ad4910d4828de383b43b86112064e3ad224b73f3d42cef9d' 
  AND token = 'B3jvwdSd+LwAX2DU6cVeCeMW4823KL+PDwfNVYT5Zvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}